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PT-141 (Bremelanotide)
€ 55,45
Don't forget the reconstitution water
Required for dissolving freeze-dried peptides.
All products are intended for laboratory research only and are not suitable for human or animal consumption. By purchasing, the buyer agrees to use these products in accordance with all applicable laws.
This substance has not been evaluated or approved by the European (EMA), American (FDA) or Dutch (MEB/IGJ) medicines authorities for any human or veterinary use. No medical, therapeutic, diagnostic or preventive use is claimed or implied.
PT-141, also known as Bremelanotide, is a synthetic melanocortin peptide analogue derived from Melanotan II. It is extensively studied within molecular, biochemical, and neuroendocrine research due to its interaction with melanocortin receptors (MC receptors) involved in central signaling pathways.
Unlike some related peptides, PT-141 is mainly investigated for its effects on the central nervous system and receptor-mediated signaling processes, making it relevant for studies of neuroendocrine communication and molecular signaling.
Within experimental models, PT-141 is often used to study melanocortin receptor activity, pathway modulation, and peptide-receptor interactions.
History of PT-141
PT-141 was developed within research on melanocortin peptides derived from α-MSH analogues, with the aim of better understanding receptor-specific signaling within the melanocortin system.
Early studies focused on interactions with central melanocortin receptors, while later studies expanded to neuroendocrine signaling, pathway coordination, and molecular communication systems.
Today, PT-141 remains an important compound in experimental peptide research, especially in studies on central receptor signaling and pathway dynamics.
PT-141 Structure and Molecular Data
Peptide Name: PT-141 (Bremelanotide)
Peptide Type: Melanocortin Analog
Sequence: Cyclic peptide derived from Melanotan II
Molecular Formula: C50H68N14O10
Molecular Weight: ~1025.2 g/mol
PT-141 is a cyclic peptide, which provides increased stability and improved receptor binding. This structure makes it well-suited for receptor-based research models.
PT-141 Study Findings
PT-141 has been extensively investigated in molecular and neuroendocrine models, with a focus on melanocortin signaling pathways.
Research shows activity related to:
• Melanocortin receptor (MC) interaction and signaling
• Central nervous system signaling pathways
• Neuroendocrine pathway modulation
• Peptide-receptor binding dynamics
Major Research Areas of PT-141
Receptor Research
Focus on melanocortin receptor binding and signaling mechanisms.
Neuroendocrine Research
Analysis of central signaling pathways and hormonal communication.
Molecular research
Study of peptide interactions and pathway modulation.
Systemic Research
Research on coordinated signaling within complex biological systems.
Scientific Relevance of PT-141
PT-141 is considered an important melanocortin research peptide for studying central receptor signaling and neuroendocrine pathway dynamics.
Due to its cyclic structure and receptor affinity, it is highly relevant for investigating peptide-receptor interactions, signal modulation and biological communication systems.
References
Hadley ME. et al. (1995). Melanocortin peptides and receptor interaction.
Hruby VJ. et al. (2001). Design and activity of melanocortin analogs.
Cone RD. (2005). Melanocortin receptors and physiological signaling.
Our Process
Frequently asked questions
Each batch is independently tested by third-party laboratories using HPLC and mass spectrometry. You can view the Certificate of Analysis (COA) of your specific batch on our lab results page.
Orders placed before 15:00 will be shipped the same day from our EU warehouse. Delivery typically takes 1–3 business days, depending on your location within Europe.