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LL-37
€ 54,45
Don't forget the reconstitution water
Required for dissolving freeze-dried peptides.
All products are intended for laboratory research only and are not suitable for human or animal consumption. By purchasing, the buyer agrees to use these products in accordance with all applicable laws.
This substance has not been evaluated or approved by the European (EMA), American (FDA) or Dutch (MEB/IGJ) medicines authorities for any human or veterinary use. No medical, therapeutic, diagnostic or preventive use is claimed or implied.
LL-37 is a synthetic antimicrobial peptide (AMP) derived from the human cathelicidin protein (hCAP-18). It is extensively studied within molecular, immunological and biochemical research for its role in innate immune defenses and cellular signaling pathways.
As the only known human cathelicidin peptide, LL-37 is of great interest in experimental models that focus on host defense, microbial interactions, and immune-related signaling. Due to its broad spectrum of action, it is often used in studies of cellular communication and biological response mechanisms.
History of LL-37
LL-37 was identified as a biologically active fragment of the human antimicrobial protein hCAP-18. Early studies focused on its role in innate immunity and antimicrobial activity, especially within epithelial and immune cell environments.
Later, research expanded to include inflammation signaling, cellular communication, and tissue-related pathway dynamics, making LL-37 an important compound within experimental immunology and peptide research.
LL-37 Structure and Molecular Data
Peptide Name: LL-37
Peptide Type: Antimicrobial Peptide (AMP)
Sequence: 37-amino acid peptide derived from hCAP-18
Molecular Formula: C205H340N60O53
Molecular Weight: ~4493.3 g/mol
LL-37 consists of a chain of 37 amino acids and forms an amphipathic structure, allowing it to interact with cell membranes, microbial systems, and signaling pathways within experimental models.
LL-37 Research Findings
LL-37 has been extensively investigated in immunological, cellular and molecular models, with a focus on host defense and signaling mechanisms.
Research shows activity related to:
• Innate immune and host-defense
signaling pathways• Antimicrobial interaction models and membrane dynamics
• Cellular signaling and communication processes
• Modulation of inflammatory pathways and biological responses
Major Research Areas of LL-37
Immunological research
Focus on innate immunity, host defense, and immune signaling.
Molecular research
Analysis of membrane interactions, peptide signaling and pathway modulation.
Cellular Research
Study of communication between cells and biological response mechanisms.
Systemic Research
Research on coordinated immune and signaling networks.
Scientific Relevance of LL-37
LL-37 is considered an important antimicrobial research peptide, with great value for studying innate immune responses and host defense systems.
By interacting with both microbial membranes and cellular signaling pathways, it is highly relevant for experimental models on immune function, inflammation signaling and biological communication.
Due to its unique role as a human cathelicidin-derived peptide, LL-37 remains an important compound in immunology, molecular biology and peptide research.
References
Zanetti M. (2004). Cathelicidins and innate immunity.
Dürr UH. et al. (2006). LL-37 structure and antimicrobial function.
Nijnik A. et al. (2009). Immunomodulatory functions of LL-37.
Our Process
Frequently asked questions
Each batch is independently tested by third-party laboratories using HPLC and mass spectrometry. You can view the Certificate of Analysis (COA) of your specific batch on our lab results page.
Orders placed before 15:00 will be shipped the same day from our EU warehouse. Delivery typically takes 1–3 business days, depending on your location within Europe.