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Melanotan 2 (MT-II)
€ 57,45
Don't forget the reconstitution water
Required for dissolving freeze-dried peptides.
All products are intended for laboratory research only and are not suitable for human or animal consumption. By purchasing, the buyer agrees to use these products in accordance with all applicable laws.
This substance has not been evaluated or approved by the European (EMA), American (FDA) or Dutch (MEB/IGJ) medicines authorities for any human or veterinary use. No medical, therapeutic, diagnostic or preventive use is claimed or implied.
Melanotan II (MT-2) is a synthetic melanocortin-peptide analogue derived from α-melanocyte-stimulating hormone (α-MSH). It is widely studied within molecular, biochemical, and receptor-based research due to its interaction with melanocortin receptors (MC receptors) involved in pigmentation and signaling pathways.
Within experimental models, Melanotan II is often used to investigate melanocortin system dynamics, receptor interaction, and pathway modulation. Due to its stability and high receptor affinity, it is a relevant compound for studies of cellular signaling and peptide-receptor interactions.
History of Melanotan II
Melanotan II was developed within research on α-MSH analogues to better understand the role of melanocortin peptides in biological signaling systems. Early studies focused on pigmentation-related pathways and receptor activity, while later research expanded to neuroendocrine signaling and molecular pathway dynamics.
Over time, MT-2 has remained an important compound in experimental peptide research, especially in studies of MC receptor signaling and regulation of pathways.
Melanotan II Structure and Molecular Data
Peptide Name: Melanotan II (MT-2)
Peptide Type: Melanocortin Analog
Sequence: Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH₂
Molecular Formula: C50H69N15O9
Molecular Weight: ~1024.2 g/mol
Melanotan II is a cyclic peptide, which provides increased stability and improved receptor binding capacity. This structure makes it particularly suitable for receptor-based research models.
Melanotan II Research Findings
Melanotan II has been extensively investigated in molecular and receptor-based models, with a focus on melanocortin signaling and pathway dynamics.
Research shows activity related to:
• Melanocortin receptor (MC receptor) interaction and signaling
• Pigmentation-related molecular pathways
• Neuroendocrine signaling and pathway modulation
• Peptide receptor binding dynamics
Major Research Areas of Melanotan II
Receptor Research
Focus on melanocortin receptor binding and signaling mechanisms.
Molecular research
Analysis of peptide interaction and pathway modulation.
Neuroendocrine Research
Study of signaling within complex biological systems.
Systemic Research
Investigation of coordinated receptor-driven responses.
Scientific Relevance of Melanotan II
Melanotan II is considered an important melanocortin research peptide, with great value for studying MC receptor signaling and peptide receptor interactions.
Due to its cyclic structure and high receptor affinity, it is highly relevant for research into molecular signaling, receptor dynamics and biological communication within experimental models.
Due to its well-defined mechanism of action, MT-2 remains an important compound in peptide research, molecular biology and receptor-based studies.
References
Hadley ME. et al. (1995). Melanocortin peptides and receptor interaction.
Hruby VJ. et al. (2001). Design and activity of melanocortin analogs.
Cone RD. (2005). Melanocortin receptors and physiological signaling.
Our Process
Frequently asked questions
Each batch is independently tested by third-party laboratories using HPLC and mass spectrometry. You can view the Certificate of Analysis (COA) of your specific batch on our lab results page.
Orders placed before 15:00 will be shipped the same day from our EU warehouse. Delivery typically takes 1–3 business days, depending on your location within Europe.